Furthermore, you should know that effect of Phenylephrine is Moderate for pregnant women and Mild for women who are breastfeeding. This drug, however, is known to cause a number of severe side effects such as high blood pressure, allergic reactions, and chest pain. 2. The FDA and the National Registry of Drug-induced Ocular Side Effects (Casey Eye Institute, Portland, Oregon) have received 11 reports of adverse systemic reactions to a single dose of topical ocular phenylephrine 10% applied in pledget form [4].There were eight men and three … These side effects may go away during treatment as your body adjusts to the medicine. Organs and systems Cardiovascular. You may report side effects to FDA at 1-800-FDA-1088. Check with your doctor as soon as possible if any of the following side effects occur while taking phenylephrine ophthalmic: Symptoms of too much medicine being absorbed into the body. If you notice any other effects, check with your healthcare professional. If any of … Significant blood pressure elevations have been reported with recommended doses of 10% ophthalmic solution. You may report side effects to the FDA at 1-800-FDA-1088. Injection: 10 mg/mL supplied as a 1 mL single dose vial. We comply with the HONcode standard for trustworthy health information -, Benadryl Dosage Charts (Infants & Children), Ophthalmic antihistamines and decongestants, Eye irritation not present before use of this medicine. Symptoms: Headache, nausea, vomiting, paranoid psychosis, hallucinations, seizures, cerebral haemorrhage, palpitation, paraesthesia, reflex bradycardia, cardiac arrhythmia (e.g. Blurred vision chest pain or discomfort difficult or labored breathing dizziness fainting fast, slow, or irregular heartbeat headache nausea or vomiting nervousness pain in the shoulders, arms, jaw, or neck pounding in the ears Some of the side-effects may be rare but serious. Side effects of phenylephrine are headache, reflex bradycardia (slow heart beat), excitability, anxiety, restlessness, high blood pressure, and rarely abnormal heart beats. This guideline covers adult patients (18 years and older) in a hospital setting and adults (18 and older) in long-term residential care. Effects of xanthoangelol B on [Ca 2+]i levels in cultured rabbit aortic smooth muscle cells treated with phenylephrine. These side-effects are possible, but do not always occur. It has a role as an alpha-adrenergic agonist, a cardiotonic drug, a mydriatic agent, a protective agent, a vasoconstrictor agent, a sympathomimetic agent and a nasal decongestant. Phenylephrine is commonly used in over-the-counter medicines to relieve a stuffy nose. Phenylephrine side effects. This may increase the chance of side effects during treatment. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Find patient medical information for Phenylephrine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Phenylephrine is used to gain temporary relief from stuffy nose, sinus, and ear symptoms caused by the allergies, common cold, flu, or other breathing illnesses such as sinusitis and bronchitis.This medication works by decreasing swelling in the nose and ears which makes breathing easier and lessens any discomfort. Do not use more often, use more sprays, or use longer than directed because doing so may increase the risk of side effects. Schedule your appointment now for safe in-person care. This content does not have an Arabic version. Phenylephrine Hcl Side Effects Burning or stinging, headache, sensitivity to light, or blurred vision may occur. Phenylephrine is a member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring. See also Warning section.Dizziness, drowsiness, headache, upset stomach, nausea, constipation, nervousness, or trouble sleeping may occur. Side Effects What are the side effects of Acetaminophen And Phenylephrine (Tylenol Sinus Congestion And Pain)?. Trouble sleeping. It is often used during surgery. Call your doctor for medical advice about side effects. This medicine may used to treat very low blood pressure or serious heart problems such as irregular heartbeat. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Periorbital pallor has been reported in preterm patients. This content does not have an English version. This site complies with the HONcode standard for trustworthy health information: verify here. Neo-Synephrine (phenylephrine ophthalmic)" Sanofi Winthrop Pharmaceuticals, New York, NY. There have been reports of serious cardiovascular reactions including ventricular arrhythmias and myocardial infarctions. Side Effects What are the side effects of Phenylephrine (Sudafed PE) ? Frequency not reported: Ventricular arrhythmias, myocardial infarction, hypertension, syncope, tachycardia, arrhythmia, palpitations, extrasystoles, reflex bradycardia, coronary artery spasm. Nasal irritation is a possible side effect when taking phenylephrine. Check with your doctor as soon as possible if any of the following side effects occur while taking phenylephrine ophthalmic: Symptoms of too much medicine being absorbed into the body - Less common with 10% solution; rare with 2.5% or weaker solution. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Dizziness; fast, irregular, or pounding heartbeat; increased sweating; increase in blood pressure; paleness; trembling; … What are some other side effects of this drug? Along with its needed effects, phenylephrine ophthalmic may cause some unwanted effects. During colds I take phenylephrine when my nose is stuffy and within 30 minutes the congestion is … Call your doctor for medical advice about side effects. pain in the shoulders, arms, jaw, or neck, pain or discomfort in chest, upper stomach, or throat. "Product Information. Mayo Clinic facts about coronavirus disease 2019 (COVID-19), Our COVID-19 patient and visitor guidelines, plus trusted health information, Mayo Clinic Health System patient vaccination updates. Mild upset stomach, trouble sleeping, dizziness, lightheadedness, headache, nervousness, shaking, or fast heartbeat may occur. Along with its needed effects, a medicine may cause some unwanted effects. If your doctor has directed you to use this medication for your condition , your doctor or pharmacist may already be aware of any possible drug interactions or side effects and may be monitoring you for them. All drugs may cause side effects. Ocular side effects due to topical ocular phenylephrine are usually of little significance unless the drug is used for prolonged periods of time. Phenylephrine is in a class of medications called nasal decongestants. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Side Effects. Check with your doctor or nurse immediately if any of the following side effects occur: Incidence not known. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dizziness. Note – seniors have increased chances to experience side effects from thi… Cerner Multum, Inc. "UK Summary of Product Characteristics." The following is a list of possible side-effects that may occur in medicines that contain Phenylephrine Hcl. Common side effectsmay include: 1. skin rash; 2. insomnia; 3. excitability, particularly in children; 4. redness under the skin; 5. loss of appetite. Advertising revenue supports our not-for-profit mission. However, many people have no side effects or only have minor side effects. Phenylephrine Ophthalmic (phenylephrine ophthalmic)." Medically reviewed by Drugs.com. O 0. This is not a comprehensive list. Frequency not reported: Eye pain and stinging on instillation, temporary blurred vision, photophobia, conjunctival allergy, reactive hyperemia, transient punctuate keratitis, lacrimation, corneal edema, pigmented aqueous floaters, rebound conjunctival vasoconstriction, rebound miosis, periorbital pallor, Frequency not reported: Blanching of skin, increased perspiration, Frequency not reported: Subarachnoid hemorrhage, headache, tremor or trembling, aneurisms. Feeling nervous and excitable. All rights reserved. The lowest GoodRx price for the most common version of phenylephrine is around $32.84, 73% off the average retail price of $122.36. All rights reserved. 1. Learn about the uses, side effects, and safety tips for phenylephrine. It works by reducing swelling of the blood vessels in the nasal passages. Please speak with your doctor if these side effects worsen or persist for a longer duration. These side effects may go away during treatment as your body adjusts to the medicine. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The chart below lists examples of possible side effects from pseudoephedrine and phenylephrine. Drug information provided by: IBM Micromedex. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. nasal mucosa, therefore systemic side effects are esentially the same as for topical ocular exposure. Applies to phenylephrine ophthalmic: ophthalmic solution. Call your doctor if you have any serious side effects when using these drugs. Portions of this document last updated: Feb. 01, 2021. Note: The above side effects are more likely to occur in children because there is a greater chance that too much of this medicine may be absorbed into the body. Check with your doctor as soon as possible if any of the following side effects occur while taking phenylephrine nasal: Symptoms of too much medicine being absorbed into the body. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special - 40% off – Mayo Clinic Diet Online. Use these dosage charts for infants and children under 12 years old: epinephrine, atropine ophthalmic, brimonidine ophthalmic, phenylephrine ophthalmic, EpiPen, Adrenalin, oxymetazoline ophthalmic, fluorometholone ophthalmic. Other brands: Mydfrin, AK-Dilate, Altafrin, Neofrin, ... +2 more. ventricular tachycardia and extrasystoles), sensation of fullness in the head and tingling of extremities. Mayo Clinic does not endorse companies or products. Akorn Inc, Buffalo Grove, IL. 3. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor or nurse immediately if any of the following side effects occur while taking phenylephrine: Copyright © 2021 IBM Watson Health. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Fast, irregular, or … Phenylephrine is not suggested for use in patients with hypertension. Also, do not use this medication for more than 3 … It is also used to relieve sinus congestion and pressure. "Product Information. Phenylephrine is given systemically primarily as sprays onto mucous membranes, i.e. If you notice any other effects, check with your healthcare professional. 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